The Evidence for Myonuclear Muscle Memory May be Murkier Than Commonly Believed
It’s commonly believed that myonuclei – the “control centers” of muscle fibers – are added to muscle fibers when fibers grow, but aren’t lost by fibers when they shrink, facilitating muscle re-growth. This is a proposed mechanism for the phenomenon of “muscle memory.” However, a recent review suggests that the data is less conclusive than people may realize.