How We Grow: Anabolic Signaling Mechanisms, Part 1
What do acute anabolic signaling mechanisms tell us about long-term growth? This guest post from Adam Tzur digs into the evidence.
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What do acute anabolic signaling mechanisms tell us about long-term growth? This guest post from Adam Tzur digs into the evidence.
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What you’re getting yourself into ~3300 words, 11-22 minute read time Key Points 1. When comparing a WIDE array of training variables (number of reps, rest periods, rep speed, and loading), muscle growth is the same if sets are taken to failure. 2. Training to failure is likely safe. Or, at the very least, there’s no direct evidence that it’s particularly dangerous. 3. Training to complete failure likely isn’t necessary to maximize growth – you can
Author’s note: This article is due for a major overhaul (partially for the reasons discussed here). There are a couple things in here I don’t entirely agree with anymore. Based on some more recent research, I’m less confident about time off resulting in enhanced hypertrophy once you resume training (though I think the mechanism is still plausible, and I’d still like to see it tested on well-trained lifters). What you’re getting yourself into ~8600 words,
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